You know that weird thing when you're on the net looking for something and you find something completely different -- and weird? I just came across a site called Opiophile (people that love opioids) who share tips and suggestions on how to get high on on opiates. Well, getting high on opiates isn't all that hard, as that's what they do, get you high, as well as act as painkillers. But these people aren't even talking about anything so obvious as Hillbilly Heroin (oxycodone), which itself is leagues below the morphine injections you get in the hospital after surgery. These "opiophiles" are talking about getting high on, of all things IMODIUM, the antidiarrheal over the counter medication! Here's a description of Imodium (generic name Loperamide) from Wikipedia: Loperamide is an opioid-receptor agonist and acts on the μ-opioid receptors in the myenteric plexus of the large intestine; by itself it does not affect the central nervous system. It works similarly to morphine, by decreasing the activity of the myenteric plexus, which in turn decreases the tone of the longitudinal and circular smooth muscles of the intestinal wall.[6][7] This increases the amount of time substances stay in the intestine, allowing for more water to be absorbed out of the fecal matter. Loperamide also decreases colonic mass movements and suppresses the gastrocolic reflex.[8]
I have a long history with Imodium -- not to get high, that's for sure -- I have used it as an antidiarrheal for Crohn's disease. It was once explained to me by a pharmacist that it is related to codeine but that the molecular structure is mirrored as well as missing a few components, so while it works on slowing down the gastro-intestinal tract like codeine, only a minuscule amount is able to pass through the blood brain barrier to effect the central nervous system, so you get the constipating effects of an opiate but without the CNS effects -- no high and can't poop! But I really hate the stuff; I find it doesn't work for me at lower doses, and if I take enough for it to work at all it works too well and my intestinal spasms don't just slow down, they stop. Makes me feel like a pregnant hippo, or like I swallowed a giant barrel cactus.
Some people who obviously can't get anything more than a tylenol from any doctor anywhere forever (probably because they have a rather suspect history of doctor hopping and abusing prescription painkillers) have come up with a way to get what little bit of opiate is present in Imodium to pass through the blood brain barrier and effect a CNS high. Apparently they add pulverized Imodium tablets to a solution of Butyl Cyanoacrylate (BC) and Polysorbate 80 (P80) in acidified water. BC is used to make those weird bandage-less bandaids--you know, the liquid bandages that you paint over a cut--and P80, a sugar alcohol found in all sorts of food products as an emulsifier. The last thing added is Insulin, a hormone that helps our cells absorb glucose from the blood.
The end result of all this weird science is to first break down Imodium into small particles through the acidic water, and to allow the nanoparticles of BC, P80 and Insulin to first deliver, then bind the opiate properties of Imodium to cells within the Central Nervous System. The preferred method of delivery is by IV injection.
I really wonder exactly how long it took for someone to figure this all out and, well, the pertinent question is WHY? There must be easier ways to get stoned. And shooting yourself full of bandaid-glue is kind of creepy if you ask me. Where exactly would you get readily available insulin? Insulin can be farmed from mice, but most of the Insulin people use nowadays for diabetes is artificial, no harm done to any animals at any stage at all. Do they have shelves of mice they feed a lot of sugar too in order to increase insulin production? Wouldn't you need a warehouse for all this equipment? Or do you just do it at the kitchen table in a frying pan?
Well, that's my weird find for the day. It just goes to show that if a person wants to get high and constipated for about two weeks straight and maybe have to go to the hospital for a high colonic enema, where there's a will there's a way!
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